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Identification and experimental validation of key extracellular proteins as potential targets in intervertebral disc degeneration

AIMS: This study aimed, through bioinformatics analysis and in vitro experiment validation, to identify the key extracellular proteins of intervertebral disc degeneration (IDD). METHODS: The gene expression profile of GSE23130 was downloaded from the Gene Expression Omnibus (GEO) database. Extracell...

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Detalles Bibliográficos
Autores principales: Zhang, Guang-Zhi, Li, Lei, Luo, Zhang-Bin, Zhang, Cang-Yu, Wang, Yong-Gang, Kang, Xue-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475329/
https://www.ncbi.nlm.nih.gov/pubmed/37661086
http://dx.doi.org/10.1302/2046-3758.129.BJR-2022-0369.R2