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Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines

IgG antibodies are important mediators of vaccine-induced immunity through complement- and Fc receptor-dependent effector functions. Both are influenced by the composition of the conserved N-linked glycan located in the IgG Fc domain. Here, we compared the anti-Spike (S) IgG1 Fc glycosylation profil...

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Detalles Bibliográficos
Autores principales: Van Coillie, Julie, Pongracz, Tamas, Šuštić, Tonći, Wang, Wenjun, Nouta, Jan, Le Gars, Mathieu, Keijzer, Sofie, Linty, Federica, Cristianawati, Olvi, Keijser, Jim B.D., Visser, Remco, van Vught, Lonneke A., Slim, Marleen A., van Mourik, Niels, Smit, Merel J., Sander, Adam, Schmidt, David E., Steenhuis, Maurice, Rispens, Theo, Nielsen, Morten A., Mordmüller, Benjamin G., Vlaar, Alexander P.J., Ellen van der Schoot, C., Roozendaal, Ramon, Wuhrer, Manfred, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475480/
https://www.ncbi.nlm.nih.gov/pubmed/37670790
http://dx.doi.org/10.1016/j.isci.2023.107619