Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions

Targeted genome editing holds great promise in biology. However, efficient genome modification, including gene knock-in (KI), remains an unattained goal in multiple cell types and loci due to poor transfection efficiencies and low target genes expression, impeding the positive selection of recombine...

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Detalles Bibliográficos
Autores principales: Deleuze, Virginie, Garcia, Leonor, Rouaisnel, Betty, Salma, Mohammad, Kinoo, Alexia, Andrieu-Soler, Charlotte, Soler, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475484/
https://www.ncbi.nlm.nih.gov/pubmed/37670779
http://dx.doi.org/10.1016/j.isci.2023.107641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475484/
https://www.ncbi.nlm.nih.gov/pubmed/37670779
http://dx.doi.org/10.1016/j.isci.2023.107641

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