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Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions
Targeted genome editing holds great promise in biology. However, efficient genome modification, including gene knock-in (KI), remains an unattained goal in multiple cell types and loci due to poor transfection efficiencies and low target genes expression, impeding the positive selection of recombine...
Autores principales: | Deleuze, Virginie, Garcia, Leonor, Rouaisnel, Betty, Salma, Mohammad, Kinoo, Alexia, Andrieu-Soler, Charlotte, Soler, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475484/ https://www.ncbi.nlm.nih.gov/pubmed/37670779 http://dx.doi.org/10.1016/j.isci.2023.107641 |
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