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Strategies for enhancing CAR T cell expansion and persistence in HIV infection

Chimeric Antigen Receptor (CAR) T cell therapies are tremendously successful in hematological malignancies and show great promise as treatment and curative strategy for HIV. A major determinant for effective CAR T cell therapy is the persistence of CAR T cells. Particularly, antigen density and targ...

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Detalles Bibliográficos
Autores principales: Rothemejer, Frederik Holm, Lauritsen, Nanna Pi, Søgaard, Ole Schmeltz, Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475529/
https://www.ncbi.nlm.nih.gov/pubmed/37671164
http://dx.doi.org/10.3389/fimmu.2023.1253395