DNA self-assembly nanoflower reverse P-glycoprotein mediated drug resistance in chronic myelogenous leukemia therapy

Introduction: Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disorder caused by the BCR-ABL chimeric tyrosine kinase. Vincristine (VCR) is widely used in leukemia therapy but is hindered by multidrug resistance (MDR). Methods: We prepared DNA nanoflower via self-assembly for the d...

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Detalles Bibliográficos
Autores principales: Zhao, Pengxuan, Zhong, Yeteng, Pan, Pengcheng, Zhang, Shasha, Tian, Yu, Zhang, Jun, Yi, Guohui, Zhao, Zhendong, Wu, Tiantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475561/
https://www.ncbi.nlm.nih.gov/pubmed/37671185
http://dx.doi.org/10.3389/fbioe.2023.1265199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475561/
https://www.ncbi.nlm.nih.gov/pubmed/37671185
http://dx.doi.org/10.3389/fbioe.2023.1265199

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