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Ribosome inactivation by Escherichia coli GTPase RsgA inhibits T4 phage

INTRODUCTION: Bacteria must combat phages, and myriad bacterial anti-phage systems have been discovered that reduce host metabolism, for example, by depleting energetic compounds like ATP and NAD(+). Hence, these systems indirectly inhibit protein production. Surprisingly, direct reduction of riboso...

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Detalles Bibliográficos
Autores principales: Fernández-García, Laura, Tomás, María, Wood, Thomas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475562/
https://www.ncbi.nlm.nih.gov/pubmed/37670987
http://dx.doi.org/10.3389/fmicb.2023.1242163