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Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions

Crimean-Congo hemorrhagic fever virus (CCHFV; family Nairoviridae) is a tick-borne pathogen that frequently causes lethal disease in humans. CCHFV has a wide geographic distribution, and cases have been reported in Africa, Asia, the Middle East, and Europe. Availability of a safe and efficacious vac...

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Detalles Bibliográficos
Autores principales: Scholte, F. E. M., Karaaslan, E., O’Neal, T. J., Sorvillo, T. E., Genzer, S. C., Welch, S. R., Coleman-McCray, J. D., Spengler, J. R., Kainulainen, M. H., Montgomery, J. M., Pegan, S. D., Bergeron, E., Spiropoulou, C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475602/
https://www.ncbi.nlm.nih.gov/pubmed/37671145
http://dx.doi.org/10.3389/fcimb.2023.1233148