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Concomitant PIK3CA and TP53 Mutations in Breast Cancer: An Analysis of Clinicopathologic and Mutational Features, Neoadjuvant Therapeutic Response, and Prognosis

PURPOSE: PIK3CA and TP53 are the most prevalently mutated genes in breast cancer (BC). Previous studies have indicated an association between concomitant PIK3CA/TP53 mutations and shorter disease-free survival. As its clinical utility remains largely unknown, we aimed to analyze the prognostic and p...

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Detalles Bibliográficos
Autores principales: Lin, Xiao-Yi, Guo, Lijuan, Lin, Xin, Wang, Yulei, Zhang, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475711/
https://www.ncbi.nlm.nih.gov/pubmed/37565929
http://dx.doi.org/10.4048/jbc.2023.26.e30