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Interferon‐expressing oncolytic adenovirus + chemoradiation inhibited pancreatic cancer growth in a hamster model

Past clinical trials of adjuvant therapy combined with interferon (IFN) alpha, fluorouracil, cisplatin, and radiation improved the 5‐year survival rate of pancreatic ductal adenocarcinoma (PDAC). However, these trials also revealed the disadvantages of the systemic toxicity of IFN and insufficient d...

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Detalles Bibliográficos
Autores principales: Shinoda, Shuhei, Sharma, Nikita S., Nakamura, Naohiko, Inoko, Kazuho, Sato‐Dahlman, Mizuho, Murugan, Paari, Davydova, Julia, Yamamoto, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475772/
https://www.ncbi.nlm.nih.gov/pubmed/37439437
http://dx.doi.org/10.1111/cas.15903