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CCL21‐Ser expression in melanoma cells recruits CCR7 (+) naïve T cells to tumor tissues and promotes tumor growth

CCL21‐Ser, a chemokine encoded by the Ccl21a gene, is constitutively expressed in the thymic epithelial cells and stromal cells of secondary lymphoid organs. It regulates immune cell migration and survival through its receptor CCR7. Herein, using CCL21‐Ser‐expressing melanoma cells and the Ccl21a‐de...

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Detalles Bibliográficos
Autores principales: Miyamoto, Megumi, Kawato, Yuki, Fujie, Ryonosuke, Kurowarabe, Kaoru, Fujiwara, Kakeru, Nobusawa, Reika, Hayashi, Ryota, Iida, Kei, Ohigashi, Izumi, Hayasaka, Haruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475776/
https://www.ncbi.nlm.nih.gov/pubmed/37421165
http://dx.doi.org/10.1111/cas.15902