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Genetic and nongenetic mechanisms for colorectal cancer evolution

The stepwise accumulation of key driver mutations is responsible for the development and malignant progression of colorectal cancer in primary sites. Genetic mouse model studies have revealed combinations of driver gene mutations that induce phenotypic changes in tumors toward malignancy. However, c...

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Detalles Bibliográficos
Autores principales: Kok, Sau Yee, Nakayama, Mizuho, Morita, Atsuya, Oshima, Hiroko, Oshima, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475778/
https://www.ncbi.nlm.nih.gov/pubmed/37357016
http://dx.doi.org/10.1111/cas.15891