A topic modeling approach reveals the dynamic T cell composition of peripheral blood during cancer immunotherapy

We present TopicFlow, a computational framework for flow cytometry data analysis of patient blood samples for the identification of functional and dynamic topics in circulating T cell population. This framework applies a Latent Dirichlet Allocation (LDA) model, adapting the concept of topic modeling...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Xiyu, Lee, Jasme, Adamow, Matthew, Maher, Colleen, Postow, Michael A., Callahan, Margaret K., Panageas, Katherine S., Shen, Ronglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475788/
https://www.ncbi.nlm.nih.gov/pubmed/37671017
http://dx.doi.org/10.1016/j.crmeth.2023.100546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475788/
https://www.ncbi.nlm.nih.gov/pubmed/37671017
http://dx.doi.org/10.1016/j.crmeth.2023.100546

Ejemplares similares