Cargando…
A topic modeling approach reveals the dynamic T cell composition of peripheral blood during cancer immunotherapy
We present TopicFlow, a computational framework for flow cytometry data analysis of patient blood samples for the identification of functional and dynamic topics in circulating T cell population. This framework applies a Latent Dirichlet Allocation (LDA) model, adapting the concept of topic modeling...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475788/ https://www.ncbi.nlm.nih.gov/pubmed/37671017 http://dx.doi.org/10.1016/j.crmeth.2023.100546 |