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Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection

Most influenza vaccines currently in use target the highly variable hemagglutinin protein to induce neutralizing antibodies and therefore require yearly reformulation. T cell-based universal influenza vaccines focus on eliciting broadly cross-reactive T-cell responses, especially the tissue-resident...

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Detalles Bibliográficos
Autores principales: Kong, Hyun-Jung, Choi, Youngwon, Kim, Eun-Ah, Chang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475829/
https://www.ncbi.nlm.nih.gov/pubmed/37670808
http://dx.doi.org/10.4110/in.2023.23.e32