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Single-cell sequencing of individual retinal organoids reveals determinants of cell-fate heterogeneity

With a critical need for more complete in vitro models of human development and disease, organoids hold immense potential. Their complex cellular composition makes single-cell sequencing of great utility; however, the limitation of current technologies to a handful of treatment conditions restricts...

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Detalles Bibliográficos
Autores principales: Tresenrider, Amy, Sridhar, Akshayalakshmi, Eldred, Kiara C., Cuschieri, Sophia, Hoffer, Dawn, Trapnell, Cole, Reh, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475847/
https://www.ncbi.nlm.nih.gov/pubmed/37671011
http://dx.doi.org/10.1016/j.crmeth.2023.100548