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Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response

BACKGROUND: Massive tumor-associated macrophage (TAM) infiltration is observed in many tumors, which usually display the immune-suppressive M2-like phenotype but can also be converted to an M1-like antitumor phenotype due to their high degree of plasticity. The macrophage polarization state is assoc...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Na, Wang, Yuan-Yuan, Wang, Jin, Bai, Wen-Juan, Miao, Nai-Jun, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476141/
https://www.ncbi.nlm.nih.gov/pubmed/37652576
http://dx.doi.org/10.1136/jitc-2023-007253