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Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response
BACKGROUND: Massive tumor-associated macrophage (TAM) infiltration is observed in many tumors, which usually display the immune-suppressive M2-like phenotype but can also be converted to an M1-like antitumor phenotype due to their high degree of plasticity. The macrophage polarization state is assoc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476141/ https://www.ncbi.nlm.nih.gov/pubmed/37652576 http://dx.doi.org/10.1136/jitc-2023-007253 |