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4-Octyl Itaconate and Dimethyl Fumarate Induce Secretion of the Anti-Inflammatory Protein Annexin A1 via NRF2

Annexin A1 is a key anti-inflammatory effector protein that is involved in the anti-inflammatory effects of glucocorticoids. 4-Octyl itaconate (4-OI), a derivative of the endogenous metabolite itaconate, which is abundantly produced by LPS-activated macrophages, has recently been identified as a pot...

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Detalles Bibliográficos
Autores principales: Diskin, Ciana, Day, Emily A., Henry, Órlaith C., Toller-Kawahisa, Juliana E., O’Neill, Luke A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476164/
https://www.ncbi.nlm.nih.gov/pubmed/37578391
http://dx.doi.org/10.4049/jimmunol.2200848