Cobalt-Catalyzed Aerobic Aminocyclization of Unsaturated Amides for the Synthesis of Functionalized γ- and δ-Lactams

[Image: see text] We report the cobalt-catalyzed aminocyclization of unsaturated N-acyl sulfonamides in the presence of oxygen to provide γ- and δ-lactam aldehydes. Use of an optically active cobalt catalyst resulted in the formation of enantiomerically enriched γ-and δ-lactam alcohols. The γ-lactam...

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Detalles Bibliográficos
Autores principales: Freis, Manuel, Balkenhohl, Moritz, Fischer, David M., Georgiev, Tony, Sarott, Roman C., Carreira, Erick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476186/
https://www.ncbi.nlm.nih.gov/pubmed/37610083
http://dx.doi.org/10.1021/acs.orglett.3c02390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476186/
https://www.ncbi.nlm.nih.gov/pubmed/37610083
http://dx.doi.org/10.1021/acs.orglett.3c02390

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