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Direct Mass Spectrometry-Based Detection and Antibody Sequencing of Monoclonal Gammopathy of Undetermined Significance from Patient Serum: A Case Study

[Image: see text] Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder characterized by the presence of a predominant monoclonal antibody (i.e., M-protein) in serum, without clinical symptoms. Here we present a case study in which we detect MGUS by liquid-chromatograph...

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Detalles Bibliográficos
Autores principales: Peng, Weiwei, den Boer, Maurits A., Tamara, Sem, Mokiem, Nadia J., van der Lans, Sjors P. A., Bondt, Albert, Schulte, Douwe, Haas, Pieter-Jan, Minnema, Monique C., Rooijakkers, Suzan H. M., van Zuilen, Arjan D., Heck, Albert J. R., Snijder, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476240/
https://www.ncbi.nlm.nih.gov/pubmed/37499263
http://dx.doi.org/10.1021/acs.jproteome.3c00330