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Optimized LC-MS/MS Method for the Detection of ppCCK(21–44): A Surrogate to Monitor Human Cholecystokinin Secretion

[Image: see text] The hormone cholecystokinin (CCK) is secreted postprandially from duodenal enteroendocrine cells and circulates in the low picomolar range. Detection of this digestion and appetite-regulating hormone currently relies on the use of immunoassays, many of which suffer from insufficien...

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Detalles Bibliográficos
Autores principales: Foreman, Rachel E., Miedzybrodzka, Emily L., Eiríksson, Finnur Freyr, Thorsteinsdóttir, Margrét, Bannon, Christopher, Wheller, Robert, Reimann, Frank, Gribble, Fiona M., Kay, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476265/
https://www.ncbi.nlm.nih.gov/pubmed/37591880
http://dx.doi.org/10.1021/acs.jproteome.3c00272