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Deciphering Protein Secretion from the Brain to Cerebrospinal Fluid for Biomarker Discovery
[Image: see text] Cerebrospinal fluid (CSF) is an essential matrix for the discovery of neurological disease biomarkers. However, the high dynamic range of protein concentrations in CSF hinders the detection of the least abundant protein biomarkers by untargeted mass spectrometry. It is thus benefic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476268/ https://www.ncbi.nlm.nih.gov/pubmed/37606934 http://dx.doi.org/10.1021/acs.jproteome.3c00366 |