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Deciphering Protein Secretion from the Brain to Cerebrospinal Fluid for Biomarker Discovery

[Image: see text] Cerebrospinal fluid (CSF) is an essential matrix for the discovery of neurological disease biomarkers. However, the high dynamic range of protein concentrations in CSF hinders the detection of the least abundant protein biomarkers by untargeted mass spectrometry. It is thus benefic...

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Detalles Bibliográficos
Autores principales:	Waury, Katharina, de Wit, Renske, Verberk, Inge M. W., Teunissen, Charlotte E., Abeln, Sanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476268/ https://www.ncbi.nlm.nih.gov/pubmed/37606934 http://dx.doi.org/10.1021/acs.jproteome.3c00366

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