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A Functional Bayesian Model for Hydrogen–Deuterium Exchange Mass Spectrometry

[Image: see text] Proteins often undergo structural perturbations upon binding to other proteins or ligands or when they are subjected to environmental changes. Hydrogen–deuterium exchange mass spectrometry (HDX-MS) can be used to explore conformational changes in proteins by examining differences i...

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Detalles Bibliográficos
Autores principales: Crook, Oliver M., Gittens, Nathan, Chung, Chun-wa, Deane, Charlotte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476270/
https://www.ncbi.nlm.nih.gov/pubmed/37582225
http://dx.doi.org/10.1021/acs.jproteome.3c00297