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Cell fragmentation in mouse preimplantation embryos induced by ectopic activation of the polar body extrusion pathway

Cell fragmentation is commonly observed in human preimplantation embryos and is associated with poor prognosis during assisted reproductive technology (ART) procedures. However, the mechanisms leading to cell fragmentation remain largely unknown. Here, light sheet microscopy imaging of mouse embryos...

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Detalles Bibliográficos
Autores principales: Pelzer, Diane, de Plater, Ludmilla, Bradbury, Peta, Eichmuller, Adrien, Bourdais, Anne, Halet, Guillaume, Maître, Jean‐Léon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476277/
https://www.ncbi.nlm.nih.gov/pubmed/37427462
http://dx.doi.org/10.15252/embj.2023114415