Direct observation of coordinated assembly of individual native centromeric nucleosomes

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Eukaryotic chromosome segregation requires the kinetochore, a megadalton‐sized machine that forms on specialized centromeric chromatin containing CENP‐A, a histone H3 variant. CENP‐A deposition requires a chaperone protein HJURP that targets it to the centromere, but it has remained unclear whether...

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Detalles Bibliográficos
Autores principales: Popchock, Andrew R, Larson, Joshua D, Dubrulle, Julien, Asbury, Charles L, Biggins, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476280/
https://www.ncbi.nlm.nih.gov/pubmed/37469281
http://dx.doi.org/10.15252/embj.2023114534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476280/
https://www.ncbi.nlm.nih.gov/pubmed/37469281
http://dx.doi.org/10.15252/embj.2023114534

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