The CUL4B‐based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho‐specific DCAFs

The paralogs CUL4A and CUL4B assemble cullin‐RING E3 ubiquitin ligase (CRL) complexes regulating multiple chromatin‐associated cellular functions. Although they are structurally similar, we found that the unique N‐terminal extension of CUL4B is heavily phosphorylated during mitosis, and the phosphor...

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Detalles Bibliográficos
Autores principales: Stier, Anna, Gilberto, Samuel, Mohamed, Weaam I, Royall, Lars N, Helenius, Jonne, Mikicic, Ivan, Sajic, Tatjana, Beli, Petra, Müller, Daniel J, Jessberger, Sebastian, Peter, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476281/
https://www.ncbi.nlm.nih.gov/pubmed/37365982
http://dx.doi.org/10.15252/embj.2022112847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476281/
https://www.ncbi.nlm.nih.gov/pubmed/37365982
http://dx.doi.org/10.15252/embj.2022112847

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