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Large-scale proximity extension assay reveals CSF midkine and DOPA decarboxylase as supportive diagnostic biomarkers for Parkinson’s disease

BACKGROUND: There is a need for biomarkers to support an accurate diagnosis of Parkinson’s disease (PD). Cerebrospinal fluid (CSF) has been a successful biofluid for finding neurodegenerative biomarkers, and modern highly sensitive multiplexing methods offer the possibility to perform discovery stud...

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Detalles Bibliográficos
Autores principales: Paslawski, Wojciech, Khosousi, Shervin, Hertz, Ellen, Markaki, Ioanna, Boxer, Adam, Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476347/
https://www.ncbi.nlm.nih.gov/pubmed/37667404
http://dx.doi.org/10.1186/s40035-023-00374-w