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Design issues in crossover trials involving patients with Parkinson’s disease

BACKGROUND AND OBJECTIVES: Crossover designs are frequently used to assess treatments for patients with Parkinson’s disease. Typically, two-period two-treatment trials include a washout period between the 2 periods and assume that the washout period is sufficiently long to eliminate carryover effect...

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Detalles Bibliográficos
Autores principales: Sparrow, David, DeMolles, Deborah, Dubaz, Ornella, Durso, Raymon, Rosner, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476358/
https://www.ncbi.nlm.nih.gov/pubmed/37670777
http://dx.doi.org/10.3389/fneur.2023.1197281