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Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

Lung cancer is prone to bone metastasis, and osteopontin (OPN) has an important significance in maintaining bone homeostasis. The goal of this study was to explore the impact of OPN level on bone metabolism and the molecular mechanism of inhibiting bone metastasis in non-small cell lung cancer (NSCL...

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Detalles Bibliográficos
Autores principales: Guo, Jing, Tong, Chang-Yong, Shi, Jian-Guang, Li, Xin-Jian, Chen, Xue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476534/
https://www.ncbi.nlm.nih.gov/pubmed/37491944
http://dx.doi.org/10.4081/ejh.2023.3631