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SUPPLEMENTATION WITH NICOTINAMIDE RIBOSIDE ATTENUATES T CELL EXHAUSTION AND IMPROVES SURVIVAL IN SEPSIS

T cell exhaustion is the main cause of sepsis-induced immunosuppression and is associated with the poor prognosis. Nicotinamide adenine dinucleotide (NAD(+)) is well known for its anti-aging effect, but its role in sepsis-induced T cell exhaustion remains to be elucidated. In the present study, usin...

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Detalles Bibliográficos
Autores principales: Zhao, Guang-ju, Yang, Xi-yu, Zhang, Chen, Dong, Wei, Dong, Fu-bo, Zhang, Jie, Chen, Xiao-Yan, Yao, Ren-qi, Xiao, Zhong, Chen, Long-wang, Yao, Yong-ming, Lu, Zhong-qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476598/
https://www.ncbi.nlm.nih.gov/pubmed/37314209
http://dx.doi.org/10.1097/SHK.0000000000002153