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Whole Exome Sequencing Reveals Genetic Variants in HLA Class II Genes Associated With Transplant-free Survival of Indeterminate Acute Liver Failure

INTRODUCTION: Indeterminate acute liver failure (IND-ALF) is a rare clinical syndrome with a high mortality rate. Lacking a known etiology makes rapid evaluation and treatment difficult, with liver transplantation often considered as the only therapeutic option. Our aim was to identify genetic varia...

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Detalles Bibliográficos
Autores principales: Liao, Tsung-Jen, Pan, Bohu, Hong, Huixiao, Hayashi, Paul, Rule, Jody A., Ganger, Daniel, Lee, William M., Rakela, Jorge, Chen, Minjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476814/
https://www.ncbi.nlm.nih.gov/pubmed/35905417
http://dx.doi.org/10.14309/ctg.0000000000000502