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Impaired autophagy activity-induced abnormal differentiation of bone marrow stem cells is related to adolescent idiopathic scoliosis osteopenia

BACKGROUND: Osteopenia has been well documented in adolescent idiopathic scoliosis (AIS). Bone marrow stem cells (BMSCs) are a crucial regulator of bone homeostasis. Our previous study revealed a decreased osteogenic ability of BMSCs in AIS-related osteopenia, but the underlying mechanism of this ph...

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Detalles Bibliográficos
Autores principales: Zhang, Hongqi, Yang, Guanteng, Li, Jiong, Xiao, Lige, Guo, Chaofeng, Wang, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476821/
https://www.ncbi.nlm.nih.gov/pubmed/36728938
http://dx.doi.org/10.1097/CM9.0000000000002165