A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice

The BAF (BRG1/BRM-associated factor) chromatin remodelling complex is essential for the regulation of DNA accessibility and gene expression during neuronal differentiation. Mutations of its core subunit SMARCB1 result in a broad spectrum of pathologies, including aggressive rhabdoid tumours or neuro...

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Detalles Bibliográficos
Autores principales: Brugmans, Aliska K., Walter, Carolin, Moreno, Natalia, Göbel, Carolin, Holdhof, Dörthe, de Faria, Flavia W., Hotfilder, Marc, Jeising, Daniela, Frühwald, Michael C., Skryabin, Boris V., Rozhdestvensky, Timofey S., Wachsmuth, Lydia, Faber, Cornelius, Dugas, Martin, Varghese, Julian, Schüller, Ulrich, Albert, Thomas K., Kerl, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477118/
https://www.ncbi.nlm.nih.gov/pubmed/37219662
http://dx.doi.org/10.1007/s10571-023-01361-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477118/
https://www.ncbi.nlm.nih.gov/pubmed/37219662
http://dx.doi.org/10.1007/s10571-023-01361-5

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