Cargando…

An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria

BACKGROUND: The artemisinins are potent and widely used antimalarial drugs that are eliminated rapidly. A simple concentration–effect pharmacometric model does not explain why dosing more frequently than once daily fails to augment parasite clearance and improve therapeutic responses in vivo. Artemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Saralamba, Sompob, Simpson, Julie A, Choosri, Noppon, White, Lisa, Pan-Ngum, Wirichada, Dondorp, Arjen M, White, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477127/
https://www.ncbi.nlm.nih.gov/pubmed/37473441
http://dx.doi.org/10.1093/jac/dkad219

Ejemplares similares