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First clinical experience with fractionated intracavitary radioimmunotherapy using [(177)Lu]Lu-6A10-Fab fragments in patients with glioblastoma: a pilot study

BACKGROUND: Following resection and standard adjuvant radio- and chemotherapy, approved maintenance therapies for glioblastoma are lacking. Intracavitary radioimmunotherapy (iRIT) with (177)Lu-labeled 6A10-Fab fragments targeting tumor-associated carbonic anhydrase XII and injected into the resectio...

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Detalles Bibliográficos
Autores principales: Roll, Wolfgang, Müther, Michael, Böning, Guido, Delker, Astrid, Warneke, Nils, Gildehaus, Franz-Josef, Schäfers, Michael, Stummer, Walter, Zeidler, Reinhard, Reulen, Hans-Jürgen, Stegger, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477153/
https://www.ncbi.nlm.nih.gov/pubmed/37665396
http://dx.doi.org/10.1186/s13550-023-01029-7