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Natural killer cells modified with a Gpc3 aptamer enhance adoptive immunotherapy for hepatocellular carcinoma

INTRODUCTION: Natural killer cells can attack cancer cells without prior sensitization, but their clinical benefit is limited owing to their poor selectivity that is caused by the lack of specific receptors to target tumor cells. In this study, we aimed to endow NK cells with the ability to specific...

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Detalles Bibliográficos
Autores principales: Zheng, Youshi, Lai, Zisen, Wang, Bing, Wei, Zuwu, Zeng, Yongyi, Zhuang, Qiuyu, Liu, Xiaolong, Lin, Kecan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477160/
https://www.ncbi.nlm.nih.gov/pubmed/37665421
http://dx.doi.org/10.1007/s12672-023-00780-6