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The Oncology Biomarker Discovery framework reveals cetuximab and bevacizumab response patterns in metastatic colorectal cancer

Precision medicine has revolutionised cancer treatments; however, actionable biomarkers remain scarce. To address this, we develop the Oncology Biomarker Discovery (OncoBird) framework for analysing the molecular and biomarker landscape of randomised controlled clinical trials. OncoBird identifies b...

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Detalles Bibliográficos
Autores principales: Ohnmacht, Alexander J., Stahler, Arndt, Stintzing, Sebastian, Modest, Dominik P., Holch, Julian W., Westphalen, C. Benedikt, Hölzel, Linus, Schübel, Marisa K., Galhoz, Ana, Farnoud, Ali, Ud-Dean, Minhaz, Vehling-Kaiser, Ursula, Decker, Thomas, Moehler, Markus, Heinig, Matthias, Heinemann, Volker, Menden, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477267/
https://www.ncbi.nlm.nih.gov/pubmed/37666855
http://dx.doi.org/10.1038/s41467-023-41011-4