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Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validation

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic disease with an unclear etiology and no effective treatment. This study aims to elucidate the pathogenic mechanism networks involving multiple targets and pathways in IPF. Extracts and metabolites of Astragalus membranaceus (AM)...

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Detalles Bibliográficos
Autores principales: Jiang, Huanyu, Zhou, Rui, An, Liping, Guo, Junfeng, Hou, Xinhui, Tang, Jiao, Wang, Fei, Du, Quanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477296/
https://www.ncbi.nlm.nih.gov/pubmed/37666859
http://dx.doi.org/10.1038/s41598-023-36944-1