Itraconazole inhibits proliferation, induces apoptosis, and reduces angiogenesis of hemangioma endothelial cells by downregulating the hedgehog signaling pathway

Infantile hemangioma (IH) is among the most prevalent benign vascular tumours in infants. The pathogenesis of IH mainly involves abnormal proliferation of vascular endothelial cells and the formation of new vessels. Itraconazole was shown to be effective in treating IH; however, the mechanism underl...

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Detalles Bibliográficos
Autores principales: Dong, Jianyong, Cui, Jun, Shi, Xuanxuan, Wang, Tao, Liu, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477473/
https://www.ncbi.nlm.nih.gov/pubmed/37674841
http://dx.doi.org/10.1016/j.heliyon.2023.e19244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477473/
https://www.ncbi.nlm.nih.gov/pubmed/37674841
http://dx.doi.org/10.1016/j.heliyon.2023.e19244

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