Human aortic smooth muscle cell regulation by METTL3 via upregulation of m6A NOTCH1 modification and inhibition of NOTCH1

BACKGROUND: Thoracic aortic dissection (TAD) is a very serious vascular condition that requires immediate treatment. Phenotypic conversion of human aortic smooth muscle cells (HASMCs) has been reported to be a causal factor for TAD development. Genetic variations affecting RNA modification may play...

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Detalles Bibliográficos
Autores principales: Yang, Jue, Fang, Miaoxian, Yu, Changjiang, Li, Zhuxiao, Wang, Qiuji, Li, Chenxi, Wu, Jinlin, Fan, Ruixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477642/
https://www.ncbi.nlm.nih.gov/pubmed/37675298
http://dx.doi.org/10.21037/atm-22-1203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477642/
https://www.ncbi.nlm.nih.gov/pubmed/37675298
http://dx.doi.org/10.21037/atm-22-1203

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