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Cell-type-specific alternative polyadenylation promotes oncogenic gene expression in non-small cell lung cancer progression

Disrupted alternative polyadenylation (APA) is frequently involved in tumorigenesis and cancer progression by regulating the gene expression of oncogenes and tumor suppressors. However, limited knowledge of tumor-type- and cell-type-specific APA events may lead to novel APA events and their function...

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Detalles Bibliográficos
Autores principales: Huang, Kexin, Zhang, Yun, Shi, Xiaorui, Yin, Zhiqin, Zhao, Weiling, Huang, Liyu, Wang, Fu, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477688/
https://www.ncbi.nlm.nih.gov/pubmed/37675185
http://dx.doi.org/10.1016/j.omtn.2023.08.005