Acyl-protein thioesterase1 alleviates senile osteoporosis by promoting osteoblast differentiation via depalmitoylation of BMPR1a

OBJECTIVE: Senile osteoporosis (SOP) is an aging-related disease. The depalmitoylating enzyme Acyl-protein thiesterase1 (APT1) is involved in disease regulation. This study explored the mechanism of APT1 in SOP. METHODS: Eight-week-old SAMP6 mice were selected as SOP models and SAMR1 mice were contr...

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Detalles Bibliográficos
Autores principales: Ji, Changjiao, Dong, Qiaoyan, Liu, Huihui, Yang, Xiaodeng, Han, Yingguang, Zhu, Bingrui, Xing, Huaixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477743/
https://www.ncbi.nlm.nih.gov/pubmed/37674692
http://dx.doi.org/10.1016/j.reth.2023.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477743/
https://www.ncbi.nlm.nih.gov/pubmed/37674692
http://dx.doi.org/10.1016/j.reth.2023.05.004

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