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Identification of the H3K36me3 reader LEDGF/p75 in the pancancer landscape and functional exploration in clear cell renal cell carcinoma

Lens epithelium-derived growth factor (LEDGF/p75) is a reader of epigenetic marks and a potential target for therapeutic intervention. Its involvement in human immunodeficiency virus (HIV) integration and the development of leukemia driven by MLL (also known as KMT2A) gene fusion make it an attracti...

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Detalles Bibliográficos
Autores principales: Zhang, Yuwei, Guo, Wei, Feng, Yangkun, Yang, Longfei, Lin, Hao, Zhou, Pengcheng, Zhao, Kejie, Jiang, Lin, Yao, Bing, Feng, Ninghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477754/
https://www.ncbi.nlm.nih.gov/pubmed/37675289
http://dx.doi.org/10.1016/j.csbj.2023.08.023