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Sequence variety in the CC’ loop of Siglec-8/9/3 determines the recognitions to sulfated oligosaccharides

Siglecs are important lectins found in different types of immune cells and function as regulatory molecules by recognizing self-associated glycans and converting extracellular interactions into signals for inhibiting immune cell functions. Although many Siglecs have been found to show broad specific...

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Detalles Bibliográficos
Autores principales: Wang, Yucheng, Peng, Yujie, Long, Rui, Shi, Peiting, Zhang, Yinghao, Kong, De-Xin, Zheng, Jinshui, Wang, Xiaocong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477811/
https://www.ncbi.nlm.nih.gov/pubmed/37675287
http://dx.doi.org/10.1016/j.csbj.2023.08.014