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CD8 T Cell‐Derived Exosomal miR‐186‐5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis

T cells play an important role in the development of focal segmental glomerulosclerosis (FSGS). The mechanism underlying such T cell‐based kidney disease, however, remains elusive. Here the authors report that activated CD8 T cells elicit renal inflammation and tissue injury via releasing miR‐186‐5p...

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Detalles Bibliográficos
Autores principales: Xu, Xiaodong, Qu, Shuang, Zhang, Changming, Zhang, Mingchao, Qin, Weisong, Ren, Guisheng, Bao, Hao, Li, Limin, Zen, Ke, Liu, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477851/
https://www.ncbi.nlm.nih.gov/pubmed/37395441
http://dx.doi.org/10.1002/advs.202301492