Cerebral Microvascular Injury Induced by Lag3‐Dependent α‐Synuclein Fibril Endocytosis Exacerbates Cognitive Impairment in a Mouse Model of α‐Synucleinopathies

The pathological accumulation of α‐synuclein (α‐Syn) and the transmission of misfolded α‐Syn underlie α‐synucleinopathies. Increased plasma α‐Syn levels are associated with cognitive impairment in Parkinson's disease, multiple system atrophy, and dementia with Lewy bodies, but it is still unkno...

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Detalles Bibliográficos
Autores principales: Zhang, Qingxi, Duan, Qingrui, Gao, Yuyuan, He, Peikun, Huang, Rui, Huang, Haifeng, Li, Yanyi, Ma, Guixian, Zhang, Yuhu, Nie, Kun, Wang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477873/
https://www.ncbi.nlm.nih.gov/pubmed/37381656
http://dx.doi.org/10.1002/advs.202301903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477873/
https://www.ncbi.nlm.nih.gov/pubmed/37381656
http://dx.doi.org/10.1002/advs.202301903

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