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CpxA/R‐Controlled Nitroreductase Expression as Target for Combinatorial Therapy against Uropathogens by Promoting Reactive Oxygen Species Generation

The antibiotic resistances emerged in uropathogens lead to accumulative treatment failure and recurrent episodes of urinary tract infection (UTI), necessitating more innovative therapeutics to curb UTI before systematic infection. In the current study, the combination of amikacin and nitrofurantoin...

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Detalles Bibliográficos
Autores principales: Ren, Hao, Zhong, Zixing, Zhou, Shuang, Wei, Yiyang, Liang, Yujiao, He, Huiling, Zheng, Zijian, Li, Mengyuan, He, Qian, Long, Tengfei, Lian, Xinlei, Liao, Xiaoping, Liu, Yahong, Sun, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477892/
https://www.ncbi.nlm.nih.gov/pubmed/37407509
http://dx.doi.org/10.1002/advs.202300938