Shear Stress Drives the Cleavage Activation of Protease‐Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells

When circulating tumor cells (CTCs) travel in circulation, they can be killed by detachment‐induced anoikis and fluidic shear stress (SS)‐mediated apoptosis. Circulatory treatment, which can make CTCs detached but also generate SS, can increase metastasis of cancer cells. To identify SS‐specific mec...

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Detalles Bibliográficos
Autores principales: Zhou, Muya, Li, Koukou, Luo, Kathy Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477893/
https://www.ncbi.nlm.nih.gov/pubmed/37395651
http://dx.doi.org/10.1002/advs.202301059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477893/
https://www.ncbi.nlm.nih.gov/pubmed/37395651
http://dx.doi.org/10.1002/advs.202301059

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