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Position-Specific Enrichment Ratio Matrix scores predict antibody variant properties from deep sequencing data
MOTIVATION: Deep sequencing of antibody and related protein libraries after phage or yeast-surface display sorting is widely used to identify variants with increased affinity, specificity, and/or improvements in key biophysical properties. Conventional approaches for identifying optimal variants typ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477941/ https://www.ncbi.nlm.nih.gov/pubmed/37478351 http://dx.doi.org/10.1093/bioinformatics/btad446 |